17 Best Anti Aging Supplements According to Science

best anti aging supplements

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In this article I am presenting 17 of the best anti-aging supplements – backed by science – that will help you slow down the passage of time.

Time is constantly passing us by. To some, time seems to fly, whereas to others it seems as if it is dragging. Whatever your perception of the passage of time may be, one thing we must all accept is that it is inevitable.

As a result, we are constantly aging and growing older, but that doesn’t mean that we can’t still look and feel youthful, healthy, and invigorated.

Growing older is no walk in the park. Everything seems to become more of a challenge, other than gaining weight, which typically, becomes easier. As unfair as it may be, it is what it is and there is no point in stewing over the inevitable.

If you’re looking to improve your quality of life, be healthier, look healthier, and live longer, there are health supplements that you can use to help fight the ill-effects of aging.

To prove it, we’re going to be looking at 17 of them right now. We might not have yet discovered the fountain of youth, but with these supplements, we believe we’ve found the next best thing.

Best Anti-Aging Supplements

Here’s a look at 17 of the best anti-aging supplements on the market right now.

1. Bakuchiol

Close up picture of Bakuchi plant with flower
Close up picture of Bakuchi plant with flower. Image source: Jayesh Pail/Flickr

The first anti-aging supplement that we have on our best anti-aging supplements list today is one that is hailed at the next retinol supplement. It’s one which few people have heard of just yet, although that will soon be changing as it grows in popularity.

Bakuchiol is a supplement which you will likely find in many a dermatologist’s supplement cabinet, and for good reason. Derived from vitamin A, it is widely regarded as one of the premium skin-care supplements currently in existence.

In fact, over the last twelve months, it has gained cult status, especially due to the fact that it has proved to be so effective when used to treat spots, blemishes, and acne.

Bakuchiol searched have been skyrocketed the past 12 months according to Google Trends.
Bakuchiol searched have been skyrocketed the past 12 months according to Google Trends.

So, what on earth is it?

Well, Bakuchiol is derived from the seeds of a plant native to Eastern Asia. The plant is known as the Babchi plant (or Bakuchi or Psoralea Corylifolia). We might only now be hearing about it, but the plant itself has been a staple ingredient used in traditional Chinese and Indian medicine for hundreds of years.

It possesses powerful anti-inflammatory, antioxidant, and anti-bacterial properties which makes it a dream come true in terms of looking after the skin. Not only does it help to prevent bacteria building up which could cause acne, but it also helps to soothe inflamed skin, and the antioxidants promote healthy skin cells, which helps to keep the skin looking and feeling younger.

It is hailed as an alternative to retinol and can help to keep the skin looking youthful and healthy, and to help slow down the natural ill-effects of aging.

☝️ You can use/consume this plant in oil form, in powder form, consume its seeds or apply it on your skin as a serum/cream. Applying it on your skin is the recommended method to use to take advantage of its anti-aging properties to the fullest.

2. PQQ

Next up we have PQQ. PQQ stands for pyrroloquinoline quinone. To make life easier and save you a great deal more time, we’ll simply refer to it as PQQ from now on.

PQQ was once upon a time, thought to be a vitamin. However, thanks to the advancements in modern medicine, science, and research, we now know that this is not the case.

PQQ is an enzyme booster, or a cofactor, which possesses vitamin-like properties. It provides powerful antioxidant effects and benefits to the body, helping to eradicate harmful toxins and free radicals that could damage our cells after subjecting them to oxidative stress.

And yes, this does include the skin cells. PQQ is especially useful because it increases mitochondria. Mitochondria are found in the core of each cell, and they are responsible for generating energy in the form of ATP.

This, in turn, makes the cells more efficient, and healthier. The healthier your cells are, the healthier you will be. This, in turn, will benefit you on the inside as well as out.

3. Apigenin

Apigenin is next to make an appearance today. Apigenin is a powerful bioflavonoid that is found naturally within a variety of herbal ingredients – primarily in chamomile.

chamomile flowers close up image
Apigenin is found primarily in chamomile. Image source: flickr

It is loaded full of antioxidants and it is actually found in particularly high dosages in chamomile tea. It helps to promote feelings of relaxation, and in higher dosages, because its antioxidant content is so high, it can even potentially help to fight illness and disease.

There is a lot of evidence to suggest that Apigenin could potentially serve as a natural supplement used in the treatment and prevention of certain cancers, which again, is due to its naturally high antioxidant content.

Apigenin supplements are commonly used by beauty looking to improve the health and appearance of their skin. This is because it has been found to help improve skin elasticity, whilst reducing the size and appearance of wrinkles.

This, combined with its powerful anti-inflammatory properties, making it one of the best anti-aging supplements for people trying to reduce the signs and symptoms associated with aging.

4. Curcumin

Recently, turmeric supplement sales shot through the roof. People began noticing just how effective turmeric supplements could be in terms of health and well-being, and the product is now more popular than ever.

Turmeric powder in a jar
Curcumin is the main ingredient of turmeric.

The main reason why turmeric (Curcuma Longa) is so healthy and beneficial is because of an active compound it contains, known as curcumin.

Curcumin functions as a natural, hugely powerful anti-inflammatory. This helps to promote skin cell health, it regenerates damaged skin cells, it eases pain and inflammation, and it can help to give the skin a healthy glow and feel.

As well as that, curcumin has also been found to speed up wound healing, and it can help to prevent acne scarring, which can make the skin look unhealthy and look older than it actually is. In the world of health and beauty, curcumin supplements are gaining popularity by the day.

Add the benefits listed above, to the fact that it is such a powerful antioxidant, it’s easy to see why curcumin is quickly emerging as one of the most popular and best anti-aging supplements on the market today.

5. Vitamin A

Now we have one of the most popular vitamins in existence when it comes to anti-aging. Yes, we’ve got vitamin A. Vitamin A is made up of a collection of compounds, including its active forms: Retinol, retinal, and retinoic acid, as well as carotenoids such as beta-carotene, which functions as an antioxidant.

If you are exposed to UV rays from the sun a lot, this can cause the skin to become dry, wrinkled, and leathery. Vitamin A is very useful because it helps to protect the skin from harmful UV rays which can slow the aesthetic signs of premature aging. In terms of your appearance, Vitamin A is especially beneficial because it has been found to promote the production of fibroblasts.

Fibroblasts are cells that are responsible for the development of tissue within the skin that help to keep it healthy and firm. This will keep the skin healthy-looking, it will keep it firm and elastic, it helps to prevent wounds and damage, and it keeps it hydrated and soft.

6. Vitamin D

Vitamin D is also known as the sunshine vitamin. The reason for this is that, when exposed to rays from the sun, a chemical process within our bodies allows us to naturally synthesize this vitamin.

Rays from the sun do not emit vitamin D as some people believe, but rather, they allow us to generate the vitamin naturally, which is just as good.

Vitamin D
Vitamin D graphic. Source: © iStock

But why is this important?

Well, because a vitamin D deficiency can affect your health in a variety of ways, especially in terms of the ill-effects of aging.

Vitamin D deficiencies can leave the skin looking pale, saggy, wrinkled, and looking older and unhealthier than it should be.

Vitamin D is a fat-soluble vitamin that can negatively impact the appearance and health of your skin. Your skin, or your epidermis, as it is scientifically known, is the largest organ in your body. Yes, your skin is actually an organ.

Vitamin D helps to prevent the signs of skin aging by lengthening the size of telomeres. Telomeres are caps of genetic material which are located on the free ends of your DNA strands. The shorter they are, the more wrinkles the skin has, the less elastic it becomes, and the unhealthier it looks.

As vitamin D helps to lengthen them, you get a good idea as to why vitamin D supplements are so beneficial for people looking to improve the appearance of their skin and fight the signs of aging.

Vitamin D also promotes healthy bones and joints as it enables calcium to be absorbed into the bones, where it strengthens them. Osteoporosis and brittle bone disease are both very common health issues experienced by people as they grow older.

⚠️ Be aware that too much Vitamin D may harm bones, not help. So, do not exceed the daily consume quantity, supplement manufacturers suggest.

7. Vitamin K

Vitamin K is one of the lesser-known vitamins on our list today. Vitamin K is another fat-soluble vitamin that plays a vital role in numerous physiological processes.

It’s good for the heart, bones, immune system, blood clotting, and much more besides. It is actually available in two different forms. You have vitamin K1, and you have vitamin K2.

K1 is found in plant-based foods such as green leafy vegetables, whereas K2 is found in meat, fish, dairy, and eggs, as well as fermented foods such as kimchi.

Best Sources of Vitamin K

Best Sources of Vitamin K
Best Source of Vitamin K – Source: VectorStock

Vitamin K2 is especially beneficial in terms of anti-aging for a couple of reasons. To begin with, it helps to divert calcium into the bones, which can help to strengthen them.

In terms of the skin, though, vitamin K2 is especially beneficial for increasing skin elasticity. It does this by preventing accumulations of calcium in elastin within the skin.

Elastin is responsible for giving skin its stretchy elastic properties. The more elastin you have, and the healthier it is, the more stretchy and elastic the skin becomes. This is very important because low levels of elastin mean that your skin is likely to look saggy and it will be more prone to wrinkles.

On top of that, the vitamin also helps to strengthen the immune system, and a healthy immune system means that you’ll be less prone to illness and disease.

8. Vitamin C

Vitamin C is probably the most common and well-known vitamin on our list today. When we think of vitamin C, we instantly think of the immune system. Vitamin C strengthens immunity and helps to keep you healthy, but it does so much more as well.

Many dermatologists and beauticians will use and prescribe vitamin C serums when it comes to reducing the signs of aging.

Vitamin C is a water-soluble vitamin that functions as a powerful antioxidant. Due to this reason, it helps the skin to regenerate itself and it encourages the synthesis of new and healthy skin cells. Dead, damaged, or unhealthy skin cells will give your skin an unhealthy appearance and will sap it of color and moisture.

As it is an antioxidant, it helps to prevent damage to the cells, including those found in the skin, caused by oxidative stress. This, in turn, will help to keep your skin firm, stretchy, hydrated, and healthy-looking. Vitamin C is also useful as it contains active ingredients that have been found to inhibit the production of melanin.

Melanin can cause the skin to look discolored and to develop dark spots and patches, that can make people look older than they actually are.

9. Zinc

Zinc is a mineral that plays an important role in numerous physiological processes going on within the human body. It’s a trace mineral, which means that we only need a small amount, that is found within each and every single cell in your body.

Native Zinc and Zinc Cube
left: a crystalline fragment of an ingot, right: sublimed-dendritic, and a 1 cm3 zinc cube for comparison by By Alchemist-hp (talk) (www.pse-mendelejew.de) – Own work, FAL, https://commons.wikimedia.org/w/index.php?curid=11660410

Zinc boosts the immune system and helps fight and prevent illness and disease. It also contributes to optimal hormone production and generation.

In terms of the skin and your appearance, though, Zinc is very important because of zinc functions as an antioxidant that can protect your cells. Cells such as those responsible for generating collagen, for example. Collagen is basically the foundation for your skin, and the more you have, the plumper and fuller the skin looks, and the firmer it becomes.

Zinc also promotes the production of new and healthy skin cells to replace damaged, dead, and unhealthy ones. In fact, your skin relies heavily on zinc for everything from wound healing and rejuvenation, to the functioning of healthy cell membranes. Zinc supplements are inexpensive and work extremely well.

10. Copper

Copper is another trace mineral that people often don’t realize is essential for optimal health and wellbeing. Many people consider copper to be one of the unsung heroes of the anti-aging world, and once you see the many benefits it provides, you’ll understand why that is.

Native copper
Copper is a shiny, reddish-brown metal. Native copper (~4 cm in size) – image source: https://en.wikipedia.org/wiki/Copper#/media/File:NatCopper.jpg

Copper peptides are now commonly used in the world of beauty and cosmetics, primarily due to their collagen-stimulating properties. Collagen helps to firm up the skin, give it moisture, plump it up, and help it look full and wrinkle-free.

The more collagen we produce, the healthier our skin will look. Copper has been found to help stimulate the production and secretion of collagen, making it great for those of you looking to enjoy smooth and healthy-looking skin.

But how does it do this?

Well, copper has been found to help activate certain enzymes, including one known as lysyl oxidase, which is responsible for the production of collagen and elastin. This, therefore, plumps up the skin, fills it out and helps to increase its elasticity, making it ideal for reducing wrinkles.

⚠️ According to WebMD.com Copper is POSSIBLY UNSAFE when taken by mouth in large amounts. Adults should consume no more than 10 mg of copper per day. 1mg of copper per day covers 100% of your DV. Symptoms of copper overdose include nausea, vomiting, bloody diarrhea, fever, stomach pain, low blood pressure, anemia, and heart problems.

11. Whey protein

Whey protein isn’t just a supplement that is beneficial for bodybuilders and people looking to bulk up. It turns out that whey protein is also very beneficial for people that are looking to reduce the signs and symptoms of aging.

whey protein
Whey protein in an unflavoured form (left) and choco flavor form (right). Image source: https://bbnutrix.com/pages/denatured-vs-un-denatured-whey-protein

But how?

Well, it is all to do with a compound known as glutathione. Glutathione is produced naturally and is one of the body’s most prominent free radical scavengers.

Basically, it seeks out free radicals and destroys them before they have the chance to negatively affect the body. As we grow older, the natural production of glutathione decreases, and our levels drop dramatically.

This, in turn, reduces immunity, it causes neurodegenerative diseases and a variety of other age-related health issues and conditions. Protein also promotes an increase in collagen production, and we know what that does in regards to your skin’s health.

12. Acetyl-L-carnitine

Up next we have acetyl L-carnitine. This is an amino acid that helps to promote healthy cells throughout the body. The amino acid is commonly found in a number of anti-aging supplements, but why?

Well, Acetyl-L-Carnitine has been found to improve cognitive health and function, making it great for the brain. As you may be aware, brain health and function often slows down as we grow older, so looking after the brain is very important.

It also helps to shuttle essential fatty acids into the mitochondria of your cells. This helps to keep your cells healthy and it increases the production of energy. This means that the amino acid helps keep your cells healthy, including your skin cells, which will help you to appear youthful.

Combine this with the brain-boosting effects of Acetyl-L-Carnitine, and it’s easy to see why it’s such a popular anti-aging supplement.

13. Collagen protein

Collagen protein is relatively new to the world of health supplementation, but don’t let that put you off, because what we do know about it so far, has been incredibly promising.

Collagen is a structural protein that basically functions as a building block for your skin, muscles, bones, joints, and connective tissue. Basically, it’s like the glue that holds everything in your body in one piece.

Collagen is the most prominent protein in your body. In fact, collagen makes up over a third of the body’s total protein.

In terms of the skin and its anti-aging benefits, collagen protein supplements are important because they contain compounds and active ingredients which boost the body’s natural collagen-producing abilities. The more collagen you can produce, the more youthful the skin will appear.

14. Polyphenols

Close-up image of red, blue and black berries which are high in polyphenols
Close-up image of red, blue and black berries which are high in polyphenols

Polyphenols function as powerful antioxidants that help to promote a variety of anti-aging benefits. Not only can they help you to appear more youthful, but they can also fight the ill effects of aging on the inside.

They are able to achieve this by destroying and removing free radicals. Free radicals are unstable molecules that attack the cells, including those in the skin, and subject them to oxidation. This damages the cells, or it can sometimes kill them or cause them to mutate, and potentially turn cancerous.

Oxidative stress caused by free radicals can cause all kinds of issues. In terms of your appearance, oxidative stress to the skin cells can cause your skin to lose its firmness and to become saggy, wrinkled, and loose.

This, in turn, will make you look older and will cause more lines and wrinkles. Polyphenols help to keep the skin cells healthy, which in turn keeps your skin healthy.

15. Ubiquinol COQ10

Ubiquinol (CoQ10-H2) is a type of COQ10 which is found to be a bit more active compound in your body. Only after you take CoQ10 (ubiquinone) does your body convert it to the active form, ubiquinol (source).

Ubiquinol helps to protect your skin cells from oxidative stress and damage. It gives your skin cell mitochondria, the energy they need to promote energy in order to function correctly.

Healthy skin cells generating plenty of energy will, therefore, give you a more youthful and healthier complexion. When we are younger, mitochondria generate energy with the help of oxygen. As we grow older, mitochondria pathways change, and skin cells, in fact, don’t get their energy from mitochondria at all.

This shift in pathways is thought to damage skin cells, which in turn causes the skin to become unhealthy. The end results in lines, wrinkles, and sagging skin. According to research COQ10 improves mitochondria function and enables your skin cells to get their energy in this way once more.

16. NAD supplements

NAD supplements function as coenzymes. They get their name because NAD is an abbreviation of Nicotinamide Adenine Dinucleotide. As it is a coenzyme, it basically enables other enzymes to function as they should.

According to research made in human subjects of the popular supplement nicotinamide riboside, a compound that has been shown in mice to restore NAD+ levels. The compound has had impressive results against some aspects of aging in mouse studies, and there is now some more data for NR in humans.

NAD is used to generate certain proteins, including collagen proteins which give the skin firmness and help plump it up. NAD supplements also promote the production of sirtuin proteins, which help to protect the body on a molecular level, from age-related decline.

NAD supplements have also shown great promise when used as cognitive health boosters for the brain.

17. Omega-3 fatty acids

Last, but certainly not least, we have omega-3 fatty acids. Omega-3 fatty acids play crucial roles in countless physiological processes. They help promote cardiovascular health, they’re great for the joints, they improve memory and cognitive health, and they’re very potent anti-inflammatories.

Foods High in omega 3 fatty acids

These healthy fats keep your cell membranes strong and healthy. The membrane influences the cell’s ability to hold and to retain water. The more water the skin cells hold, the firmer, fuller, and plumper the skin will look.

Not only that, but it will also be hydrated and so it provides natural moisturizing benefits. As omega-3 fatty acids are anti-inflammatories, they reduce the production of inflammatory compounds that are involved in the aging process. Again, this can influence how the skin looks and how it feels.

Best Anti Aging Supplements – Conclusion

A long list isn’t it? Before I close down this article, I just need to emphasize on the fact that if you don’t exercise and in general follow a healthy lifestyle, these supplements will now help much. Now, if you exercise, follow a healthy lifestyle and take these supplements (maybe some of them at least) then you will see tremendous results.

If you enjoyed reading my article about the Best Antiaging Supplements for 2020, then I would really appreciate if you shared the article. It means a lot to me.

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